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A delicious Zesty Southern Chicken Spaghetti Bake served in a casserole dish topped with melted cheese and garnished with fresh herbs.

Zesty Southern Chicken Spaghetti Bake: A Comfort Food Masterpiece

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Experience the ultimate comfort food with our Zesty Southern Chicken Spaghetti Bake. This spicy, cheesy casserole combines tender shredded chicken, flavorful spices, and perfectly cooked pasta into a hearty and satisfying dish that bursts with Southern flavors. Ideal for family dinners or entertaining guests, this baked spaghetti is guaranteed to become a new favorite.

  • Total Time: 55 minutes
  • Yield: 6 servings

Ingredients

Scale
  • 3 cups cooked spaghetti
  • 2 cups cooked, shredded chicken (rotisserie or cooked at home)
  • 1 can diced tomatoes with green chilies (10 oz)
  • 1 cup shredded cheddar cheese
  • 1 cup shredded Monterey Jack cheese
  • 1/2 cup chopped green onions
  • 1/2 cup chopped bell peppers (optional for added color and flavor)
  • 1/2 teaspoon smoked paprika
  • 1 teaspoon cumin
  • 1 teaspoon chili powder
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • Salt and black pepper to taste
  • 1/2 cup creamy sour cream or Greek yogurt
  • 2 tablespoons olive oil

Instructions

  1. Cook the spaghetti until al dente, then drain and set aside. Prepare and shred the chicken if not using rotisserie.
  2. In a large bowl, combine cooked spaghetti, shredded chicken, diced tomatoes with green chilies, green onions, bell peppers, smoked paprika, cumin, chili powder, garlic powder, onion powder, salt, and pepper. Mix well.
  3. Stir in sour cream or Greek yogurt to add creaminess. Transfer the mixture to a greased baking dish.
  4. Sprinkle shredded cheddar and Monterey Jack cheeses evenly over the top.
  5. Preheat the oven to 375°F (190°C). Bake for 20-25 minutes until cheese is melted and bubbly. For a golden crust, broil for an additional 2-3 minutes.
  6. Remove from oven, let rest for a few minutes, garnish with chopped green onions, and serve hot.

Notes

  • Feel free to add sliced jalapeños or hot sauce for extra spice.
  • You can substitute shredded chicken with cooked shrimp, tofu, or ground beef for variation.
  • Use gluten-free pasta for a gluten-free version.
  • This dish can be prepared ahead and refrigerated overnight before baking.
  • Author: Emma Bloomfield
  • Prep Time: 30 minutes
  • Cook Time: 25 minutes
  • Category: Dinner
  • Method: Baking
  • Cuisine: Southern
  • Diet: High-Protein

Nutrition

  • Serving Size: 1 serving
  • Calories: 520 kcal Kcal
  • Sugar: 8 g
  • Sodium: 900 mg
  • Fat: 25 g
  • Saturated Fat: 12 g
  • Unsaturated Fat: 10 g
  • Trans Fat: 0 g
  • Carbohydrates: 55 g
  • Fiber: 4 g
  • Protein: 35 g
  • Cholesterol: 100 mg